Dye Curves

Dye dilution curves in congenital heart disease.

The need for methods capable of detecting and estimating roughly the size of congenital cardiac defects has increased with the recent rapid developments in cardiac surgery. The application of dye dilution technique to the study of these patients is largely due to the extensive work of Wood and his colleagues at the Mayo Clinic since 1950. However, although the development of these techniques re...

On-line computation of cardiac output from dye dilution curves.

• Calculation of cardiac output from dye dilution curves as described by Hamilton has been well verified.' 3 The technique of calculating the cardiac output with the use of a planimeter or replotting on log paper is tedious and-often inexact. Furthermore, the necessary long delay between the dye injection and the availability of the result has limited the use of this technique in medical resear...

The use of indigo carmine for dye dilution curves.

Investigation of the properties of indigo carmine reveals that it may be more suitable than the dye, T-1824, for circulator}' studies that are now commonly carried out using the dye dilution principle of Stewart and Hamilton. Comparison is made of simultaneous dilution curves of indigo carmine and radioactive iodinated serum albumin. Apparently, indigo carmine is bound to protein firmly enough ...

Assessment of mitral regurgitation by dye dilution curves.

Hering (1829, 1832) obtained circulation times by detecting injected samples of potassium ferrocyanide by the Prussian Blue reaction, as quoted by Dow (1956). Stewart (1894) extended the work of Hering and was able to measure the cardiac output by a quantitative determination of the dilution of a solution of salt injected intravenously. It has taken many years since Stewart's time for the indic...

Dye dilution curves in cyanotic congenital heart disease.